Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815374 | 0.90 | LTB4R2 (0.43) | LTB4R2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3807191 | 0.89 | PTGDR2 (0.48) | LTB4R2PTGDR2MDM2MEN1KMT2A | |
| SCHEMBL3807457 | 0.89 | MLYCD (0.42) | LTB4R2PTGDR2MDM2MEN1KMT2A | |
| SCHEMBL3814858 | 0.88 | LTB4R2 (0.44) | LTB4R2PTGDR2MDM2MEN1KMT2A | |
| SCHEMBL3816913 | 0.87 | LTB4R2 (0.42) | LTB4R2MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3811519 | 0.87 | BACE1 (0.41) | LTB4R2PTGDR2MDM2MEN1KMT2A | |
| SCHEMBL2157665 | 0.87 | LTB4R2 (0.44) | LTB4R2PTGDR2MDM2MEN1KMT2A | |
| SCHEMBL3815444 | 0.84 | MEN1 (0.40) | LTB4R2MEN1KMT2AMAPT | |
| SCHEMBL3815298 | 0.84 | CPB1 (0.41) | PTGDR2MEN1KMT2ABACE1 | |
| SCHEMBL3809448 | 0.84 | LTB4R2 (0.38) | LTB4R2PTGDR2MDM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |