SCHEMBL21084882

SCHEMBL21084882

CC(c1ccccc1)(c1cccc(-c2ccc(O)cc2)c1)c1cccc(-c2ccc(O)cc2)c1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.66
ESR2 Q92731 8/20 0.66
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
MMP3 P08254 1/20 0.54
BCL2L1 Q07817 1/20 0.54
HSD17B1 P14061 2/20 0.52
HSD17B2 P37059 2/20 0.52
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
ABL1 P00519 2/20 0.48
ABCB1 P08183 2/20 0.48
BCR P11274 2/20 0.48
PTPN1 P18031 2/20 0.46
CYP2C9 P11712 1/20 0.45
PTPN5 P54829 1/20 0.45
KIF11 P52732 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12004653 0.95 ESR1 (0.62) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL10758787 0.87 ESR1 (0.79) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL11223777 0.83 ESR1 (0.68) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL3816403 0.83 RXRA (0.64) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL1513832 0.83 RXRA (0.64) ESR1ESR2MEN1KMT2AMMP3
Phenol SCHEMBL28874154 0.81 RXRA (0.62) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL27277 0.80 ESR1 (1.00) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL8031149 0.80 ESR1 (1.00) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL12005093 0.80 ESR2 (0.58) ESR1ESR2MEN1KMT2AMMP3
SCHEMBL23861493 0.79 ESR1 (0.56) ESR1ESR2MEN1KMT2AMMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001759-B2 Resin composition, and pre-preg, metal-clad laminate, and printed circuit board prepared using the same TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2021-05-11 US disclosed
US-20190203123-A1 RESIN COMPOSITION, AND PRE-PREG, METAL-CLAD LAMINATE, AND PRINTED CIRCUIT BOARD PREPARED USING THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2019-07-04 US disclosed