Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809662 | 0.88 | ALDH1A1 (0.38) | TSPOPTGER1TP53RIPK1MEN1 | |
| SCHEMBL3809097 | 0.88 | LTB4R2 (0.41) | PTGER1TP53RIPK1MEN1KMT2A | |
| SCHEMBL3809827 | 0.87 | MAPT (0.37) | PTGER1TP53RIPK1MEN1KMT2A | |
| SCHEMBL3807289 | 0.86 | RIPK1 (0.41) | PTGER1TP53RIPK1 | |
| SCHEMBL3810045 | 0.86 | PTGER1 (0.35) | PTGER1MEN1KMT2ANR3C1 | |
| SCHEMBL3817267 | 0.86 | S1PR1 (0.43) | PTGER1TP53RIPK1 | |
| SCHEMBL2157860 | 0.85 | TSPO (0.46) | TSPOMEN1KMT2A | |
| SCHEMBL3809719 | 0.83 | KMT2A (0.39) | TSPOMEN1KMT2A | |
| SCHEMBL3807989 | 0.82 | TSPO (0.46) | TSPOMEN1KMT2ALTB4R2 | |
| SCHEMBL3812670 | 0.81 | TP53 (0.34) | PTGER1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |