Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158259 | 0.87 | MEN1 (0.40) | PTGER1KDM4EMEN1KMT2ATAS2R14 | |
| SCHEMBL3816732 | 0.86 | TSPO (0.42) | PTGER1NR3C1MEN1KMT2A | |
| SCHEMBL3811206 | 0.85 | HSD17B1 (0.36) | KMT2ANPC1RAB9ATAS2R14 | |
| SCHEMBL3807325 | 0.84 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3812133 | 0.84 | RAB9A (0.35) | MEN1KMT2ANPC1RAB9AP2RY14 | |
| SCHEMBL3809097 | 0.83 | LTB4R2 (0.41) | PTGER1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL3809662 | 0.83 | ALDH1A1 (0.38) | PTGER1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL3809827 | 0.82 | MAPT (0.37) | PTGER1KDM4ENR3C1MEN1KMT2A | |
| SCHEMBL2878959 | 0.82 | TSHR (0.40) | KDM4ETSHRMEN1KMT2ANPC1 | |
| SCHEMBL3807289 | 0.81 | RIPK1 (0.41) | PTGER1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |