Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cresol SCHEMBL15512405 | 0.87 | ACHE (0.39) | ESR2ESR1NUDT1BACE1HSP90AA1 | |
| Ethane SCHEMBL27512684 | 0.84 | NUDT1 (0.40) | NUDT1BACE1HSP90AA1GAAPTGS2 | |
| SCHEMBL16581383 | 0.84 | PTPN5 (0.41) | ESR2NUDT1BACE1HSP90AA1GAA | |
| Ethane SCHEMBL28160570 | 0.82 | HSD17B1 (0.41) | ESR2NUDT1BACE1HSP90AA1GAA | |
| SCHEMBL18948598 | 0.81 | NUDT1 (0.42) | NUDT1BACE1HSP90AA1PTGS2S1PR1 | |
| P-Cresol SCHEMBL15511935 | 0.79 | ACHE (0.41) | ESR2ESR1NUDT1BACE1HSP90AA1 | |
| SCHEMBL27936315 | 0.78 | NUDT1 (0.43) | ESR2ESR1NUDT1BACE1HSP90AA1 | |
| Ethane SCHEMBL28119304 | 0.78 | NUDT1 (0.44) | ESR2ESR1NUDT1BACE1HSP90AA1 | |
| SCHEMBL2718435 | 0.78 | NUDT1 (0.51) | ESR2ESR1NUDT1BACE1HSP90AA1 | |
| SCHEMBL9644050 | 0.78 | NUDT1 (0.51) | ESR2ESR1NUDT1BACE1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375461-B1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | HONSHU CHEMICAL IND (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6872858-B2 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20040049086-A1 | Diphenol and process for producing the same | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1375461-A1 | DIPHENOL AND PROCESS FOR PRODUCING THE SAME | Honshu Chemical Industry Co. Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049086-A1 | Diphenol and process for producing the same | CYP1A1, AHR, CYP2E1 | ESR2 940/4885ESR1 489/4885NUDT1 914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.