Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383373 | 0.88 | ITGB3 (0.40) | ITGB3ITGAVITGA2BUSP30HDAC8 | |
| SCHEMBL381766 | 0.84 | DRD2 (0.42) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382189 | 0.84 | ITGB3 (0.50) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL7650900 | 0.84 | ITGB3 (0.44) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL6496356 | 0.84 | HDAC1 (0.41) | DRD2DRD3 | |
| SCHEMBL382694 | 0.84 | ITGB3 (0.46) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL383236 | 0.83 | ITGB3 (0.43) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL383136 | 0.83 | DRD2 (0.41) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL383666 | 0.83 | ITGB3 (0.46) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382101 | 0.82 | ITGB3 (0.46) | DRD2DRD3ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |