Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGAV | P06756 | 4/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383666 | 0.96 | ITGB3 (0.46) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383096 | 0.90 | ITGB3 (0.47) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382824 | 0.90 | ITGB3 (0.48) | ITGB3ITGAVITGA2BSMN1; SMN2ALDH1A1 | |
| SCHEMBL6497838 | 0.88 | ITGB3 (0.42) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL383159 | 0.86 | ITGB3 (0.44) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6499251 | 0.86 | SFRP1 (0.42) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL382191 | 0.85 | ITGB3 (0.53) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL383136 | 0.85 | DRD2 (0.41) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL381828 | 0.84 | DRD2 (0.43) | ITGB3ITGAVITGA2BDRD2DRD3 | |
| SCHEMBL6497223 | 0.83 | DRD2 (0.41) | DRD2DRD3SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |