Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382400 | 0.91 | ITGB3 (0.38) | ITGB3ITGAVITGA2BKDM1AMAOA | |
| SCHEMBL381719 | 0.87 | SYK (0.40) | DRD2DRD3ITGB3ITGAVPRMT5 | |
| SCHEMBL6499250 | 0.87 | VCP (0.40) | DRD2DRD3ITGB3ITGAVHDAC1 | |
| SCHEMBL383138 | 0.86 | ITGB3 (0.43) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382189 | 0.85 | ITGB3 (0.50) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382988 | 0.84 | PRMT5 (0.38) | DRD2DRD3ITGB3ITGAVPRMT5 | |
| SCHEMBL381828 | 0.83 | DRD2 (0.43) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382569 | 0.82 | ITGB3 (0.43) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL383666 | 0.82 | ITGB3 (0.46) | DRD2DRD3ITGB3ITGAVITGA2B | |
| SCHEMBL382567 | 0.80 | ITGB3 (0.55) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |