Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819010 | 0.81 | RNF4 (0.47) | CNR2CNR1DRD2DRD3F2 | |
| SCHEMBL3819226 | 0.80 | CNR1 (0.40) | CNR2CNR1DRD2DRD3GAA | |
| SCHEMBL27594337 | 0.78 | CNR1 (0.41) | CNR2CNR1DRD2DRD3GAA | |
| SCHEMBL3819221 | 0.78 | CHRM2 (0.44) | CNR2CNR1DRD2DRD3F2 | |
| SCHEMBL3821795 | 0.75 | GRIN2A (0.41) | CNR2CNR1F2OPRM1 | |
| SCHEMBL3824522 | 0.74 | CHRM1 (0.47) | CNR2CNR1DRD2DRD3LMNA | |
| SCHEMBL7835750 | 0.73 | ALDH1A1 (0.45) | ALDH1A1OPRM1SMN1; SMN2 | |
| SCHEMBL3053871 | 0.72 | CNR2 (0.41) | CNR2CNR1DRD2DRD3 | |
| SCHEMBL20870842 | 0.71 | CNR2 (0.57) | CNR2CNR1GAALMNAALDH1A1 | |
| SCHEMBL4735333 | 0.70 | ALDH1A1 (0.48) | DRD2DRD3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |