Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737099 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL3819010 | 0.78 | RNF4 (0.47) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL3819221 | 0.75 | CHRM2 (0.44) | MEN1KMT2ACHRM2CHRM1CHRM3 | |
| SCHEMBL4736992 | 0.74 | MEN1 (0.43) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL4734150 | 0.72 | KMT2A (0.48) | ALDH1A1LMNAMEN1KMT2ACHRM2 | |
| SCHEMBL3053871 | 0.72 | CNR2 (0.41) | CHRM2CHRM1CHRM3DRD2DRD3 | |
| SCHEMBL27594337 | 0.71 | CNR1 (0.41) | ALDH1A1NPC1RAB9ATDP1MAPK1 | |
| SCHEMBL3824522 | 0.71 | CHRM1 (0.47) | ALDH1A1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL4737670 | 0.71 | SMN1; SMN2 (0.46) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL3819014 | 0.70 | CNR2 (0.46) | ALDH1A1LMNADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |