Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819929 | 1.00 | LMNA (0.44) | LMNACYP2C19SCN4ASCN5ATSHR | |
| SCHEMBL29137878 | 0.80 | CDK1 (0.37) | — | |
| SCHEMBL6649379 | 0.77 | L3MBTL1 (0.41) | LMNATSHRCYP3A4HTR2AHTR2B | |
| SCHEMBL8947859 | 0.76 | PARP1 (0.35) | HTR2AHTR2B | |
| SCHEMBL10433858 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL10433859 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL10434090 | 0.75 | CDK1 (0.30) | — | |
| SCHEMBL10434092 | 0.75 | CDK1 (0.30) | — | |
| SCHEMBL10434089 | 0.75 | CDK1 (0.30) | — | |
| SCHEMBL9792998 | 0.75 | CYP2C19 (0.50) | LMNACYP2C19SCN4ASCN5ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | claimed |
| EP-0619311-A1 | PROCESS FOR OBTAINING BENZOXAZINES USEFUL FOR THE SYNTHESIS OF OFLOXACIN, LEVOFLOXACIN AND DERIVATIVES THEREOF | DERIVADOS DEL ETILO, S.A. (ES) | 1994-10-12 | — | — | EP | claimed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | claimed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-1367132-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE PROPOXYANILINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2009-08-12 | — | — | EP | disclosed |
| US-7217560-B2 | Process for preparation of optically active propoxyaniline derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-20040077060-A1 | Process for preparation optically active propoxyaniline derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| EP-1367132-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE PROPOXYANILINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-5521310-A | Process to obtain benzoxazines to be used for the synthesis of ofloxazine, levofloxazine and derivatives | DERIVADOS DEL ETILO, S.A. (ES) | 1996-05-28 | — | — | US | disclosed |
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0619311-A1 | PROCESS FOR OBTAINING BENZOXAZINES USEFUL FOR THE SYNTHESIS OF OFLOXACIN, LEVOFLOXACIN AND DERIVATIVES THEREOF | DERIVADOS DEL ETILO, S.A. (ES) | 1994-10-12 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |