Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084896 | 0.88 | PARP1 (0.35) | PARP1PARP3 | |
| SCHEMBL6650609 | 0.85 | KDM4E (0.35) | ALDH1A1KDM4EMAPTCRHBPCRHR2 | |
| SCHEMBL6649379 | 0.83 | L3MBTL1 (0.41) | ALDH1A1KDM4EMAPTHTR2AHTR2C | |
| SCHEMBL29025196 | 0.79 | MAPT (0.40) | ALDH1A1KDM4EMAPTCRHBPCRHR2 | |
| SCHEMBL10433956 | 0.79 | HTR2C (0.43) | ALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL24180091 | 0.77 | FEN1 (0.41) | HTR2AHTR2CHTR2BALOX5APFEN1 | |
| SCHEMBL3819931 | 0.76 | LMNA (0.44) | HTR2AHTR2B | |
| SCHEMBL3819929 | 0.76 | LMNA (0.44) | HTR2AHTR2B | |
| SCHEMBL29398924 | 0.76 | ALOX5AP (0.37) | ALDH1A1KDM4EMAPTCRHBPCRHR2 | |
| SCHEMBL1707536 | 0.76 | ALOX5AP (0.37) | ALDH1A1KDM4EMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516911-A | Fluorescent intracellular calcium indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-05-14 | — | — | US | disclosed |