Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810932 | 0.87 | HDAC1 (0.47) | PKMHTTSMN1; SMN2 | |
| SCHEMBL3809230 | 0.83 | HRH3 (0.39) | KCNH2HRH3SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3456155 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL3815128 | 0.79 | GRIA2 (0.36) | AVPR2AVPR1AKCNH2HRH3SMN1; SMN2 | |
| SCHEMBL3814550 | 0.78 | CCR5 (0.43) | HRH3PKMHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3808812 | 0.78 | AOC3 (0.39) | HRH3HTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3811382 | 0.78 | KMT2A (0.43) | HTTALDH1A1HPGD | |
| SCHEMBL3813715 | 0.78 | HPGD (0.54) | HRH3SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL3819938 | 0.77 | HSD11B1 (0.53) | KCNH2HRH3CPT2CPT1ASMN1; SMN2 | |
| SCHEMBL3811229 | 0.76 | NSD2 (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124598-A1 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | HIGH POINT PHARMACEUTICALS, LLC | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124598-A1 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | HSD11B1, HSD11B2, HSD3B1 | AVPR2 861/4885AVPR1A 878/4885KCNH2 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.