Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823366 | 0.93 | KDM4E (0.62) | KDM4EPOLBKDM4ACHRM1MEN1 | |
| SCHEMBL19183449 | 0.81 | ALOX5 (0.48) | KDM4EPOLBKDM4AL3MBTL1MAPT | |
| Phenylacetic Acid SCHEMBL1829196 | 0.81 | AKR1B1 (0.59) | POLBKDM4AAKR1B1MEN1KMT2A | |
| SCHEMBL3954433 | 0.79 | KDM4E (0.62) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL10279459 | 0.78 | KDM4E (0.70) | KDM4EPOLBCHRM1MEN1KMT2A | |
| SCHEMBL27410877 | 0.77 | ALDH1A1 (0.55) | KDM4EPOLBKDM4ACHRM1MEN1 | |
| Phenylacetic Acid SCHEMBL29527733 | 0.77 | AKR1B1 (0.59) | AKR1B1LMNAL3MBTL1HTTALDH1A1 | |
| SCHEMBL12812894 | 0.77 | KDM4E (0.61) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL6756399 | 0.76 | KDM4E (0.59) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL19105213 | 0.76 | HCAR2 (0.51) | AKR1B1LMNAL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802290-A4 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTIMENTS INC (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1802290-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP Investiments Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006041506-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2006-04-20 | — | — | WO | disclosed |