Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL3820170 | 0.93 | KDM4E (0.55) | KDM4EPOLBKDM4ACHRM1MEN1 | |
| SCHEMBL3954433 | 0.85 | KDM4E (0.62) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL10279459 | 0.84 | KDM4E (0.70) | KDM4EPOLBCHRM1MEN1KMT2A | |
| SCHEMBL27410877 | 0.83 | ALDH1A1 (0.55) | KDM4EPOLBKDM4ACHRM1MEN1 | |
| SCHEMBL12812894 | 0.83 | KDM4E (0.61) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL6756399 | 0.82 | KDM4E (0.59) | KDM4ECHRM1MEN1KMT2ALMNA | |
| SCHEMBL585944 | 0.81 | HCAR2 (0.51) | LMNAL3MBTL1HCAR2TDP1HSD17B10 | |
| SCHEMBL19105213 | 0.81 | HCAR2 (0.51) | LMNAL3MBTL1HCAR2TDP1HSD17B10 | |
| SCHEMBL19183449 | 0.81 | ALOX5 (0.48) | KDM4EPOLBKDM4AL3MBTL1MAPT | |
| SCHEMBL10427476 | 0.81 | CHRM1 (0.49) | KDM4EPOLBCHRM1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014505-A2 | BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-1802290-A4 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTIMENTS INC (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008014505-A2 | BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| EP-1802290-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP Investiments Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006041506-A2 | SOLUBILIZING AGENTS FOR ACTIVE OR FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2006-04-20 | — | — | WO | disclosed |
| US-20050152858-A1 | Solubilizing agents for active or functional organic compounds | ISP INVESTMENTS INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050152858-A1 | Solubilizing agents for active or functional organic compounds | MITF, TYR, MMS19 | KDM4E 1583/4885POLB 181/4885KDM4A 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.