Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.47 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498526 | 1.00 | GPR132 (0.52) | GPR132CHRNA7L3MBTL1CYP3A4ITGB1 | |
| SCHEMBL2356597 | 0.89 | CYP3A4 (0.51) | GPR132L3MBTL1CYP3A4ITGB1ITGA4 | |
| SCHEMBL7758997 | 0.86 | ITGB3 (0.58) | ITGB1ITGA4CTSKFAAHITGB3 | |
| SCHEMBL844471 | 0.86 | ITGB3 (0.58) | ITGB1ITGA4CTSKFAAHITGB3 | |
| SCHEMBL2185240 | 0.86 | ITGB3 (0.58) | ITGB1ITGA4CTSKFAAHITGB3 | |
| SCHEMBL4966319 | 0.85 | ITGB3 (0.52) | GPR132ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL753981 | 0.84 | GPR132 (0.56) | GPR132CYP3A4ITGA4CMKLR2CMKLR1 | |
| SCHEMBL9557602 | 0.83 | GPR132 (0.56) | GPR132CHRNA7CYP3A4CMKLR2CMKLR1 | |
| SCHEMBL5634425 | 0.83 | GPR132 (0.58) | GPR132CYP3A4CTSKCMKLR2CMKLR1 | |
| SCHEMBL5634418 | 0.83 | GPR132 (0.58) | GPR132CYP3A4CTSKCMKLR2CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |