SCHEMBL382048

SCHEMBL382048

CC(C)(C)OOC(=O)C1CCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
BTK Q06187 1/20 0.39
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
ATM Q13315 1/20 0.35
HSD17B10 Q99714 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
HRH3 Q9Y5N1 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382706 0.96 ADRB2 (0.40) SMN1; SMN2TDP1HTTKMT2ABTK
SCHEMBL382062 0.94 CES2 (0.41) SMN1; SMN2TDP1HTTKMT2AADRB2
SCHEMBL22775616 0.94 CES2 (0.41) SMN1; SMN2TDP1HTTKMT2AADRB2
SCHEMBL383633 0.91 TSHR (0.36) SMN1; SMN2TDP1HTTKMT2AADRB2
SCHEMBL317158 0.91 TSHR (0.36) SMN1; SMN2TDP1HTTKMT2AADRB2
SCHEMBL28854293 0.83 LMNA (0.37) SMN1; SMN2TDP1KMT2ABTKHSD17B10
SCHEMBL29120025 0.83 ADRB2 (0.41) SMN1; SMN2TDP1HTTKMT2ABTK
SCHEMBL22775619 0.82 ADRB2 (0.41) SMN1; SMN2TDP1HTTKMT2ABTK
SCHEMBL9344467 0.82 ADRB2 (0.41) SMN1; SMN2TDP1HTTKMT2ABTK
SCHEMBL2201861 0.81 SMN1; SMN2 (0.54) SMN1; SMN2TDP1HTTKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110753726-B Polypropylene composition with excellent surface appearance 博里利斯股份公司 2022-05-03 CN disclosed
CN-110520168-B Soft polypropylene compositions with improved properties 北欧化工公司 2021-12-14 CN disclosed
CN-113242793-A Biaxially oriented polypropylene film with improved surface properties 博里利斯股份公司 2021-08-10 CN disclosed
CN-107428884-B Process for mixing an olefin polymer with reactants 博里利斯股份公司 2020-11-13 CN disclosed
CN-110753726-A Polypropylene composition with excellent surface appearance 博里利斯股份公司 2020-02-04 CN disclosed
CN-107075014-B Long chain branched polypropylene for membrane applications 博里利斯股份公司 2019-12-06 CN disclosed
WO-2017173975-A1 METHOD FOR SYNTHESIZING COMPOUND CONTAINING NON-TERMINAL DOUBLE BOND 中国科学院福建物质结构研究所 2017-10-12 WO disclosed
EP-1853426-B1 MULTILAYER STRUCTURES BOREALIS TECH OY (FI) 2015-11-04 EP disclosed
EP-2220133-B1 POLYPROPYLENE COPOLYMER BOREALIS TECH OY (FI) 2012-01-25 EP disclosed
US-20100292410-A1 Polypropylene Copolymer BOREALIS TECHNOLOGY OY (FI) 2010-11-18 US disclosed
EP-1294782-B1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS POLYOLEFINE GMBH (AT) 2007-01-10 EP disclosed
US-20060276581-A1 Plastic products with high strength and flexibility AMI AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) 2006-12-07 US disclosed
WO-2006079449-A1 MULTILAYER STRUCTURES BOREALIS TECHNOLOGY OY (FI) 2006-08-03 WO disclosed
EP-1683631-A1 Multilayer structures Borealis Technology OY (FI) 2006-07-26 EP disclosed
US-6797778-B2 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AU) 2004-09-28 US disclosed
EP-1391482-A1 Polypropylene composition Borealis GmbH (AT) 2004-02-25 EP disclosed
US-20030176590-A1 Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance BOREALIS GMBH (AT) 2003-09-18 US disclosed
EP-1294782-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE Borealis GmbH (AT) 2003-03-26 EP disclosed
EP-1167404-A1 Polyolefin products with improved toughness, strength and heat resistance Borealis GmbH (AT) 2002-01-02 EP disclosed
WO-2001098385-A1 USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE BOREALIS GMBH (AT) 2001-12-27 WO disclosed