SCHEMBL3820539

SCHEMBL3820539

NCCNc1[nH]c(=O)[nH]c(=O)c1Cl

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 13/20 0.56
▸ GPR84 Q9NQS5 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6571780 0.79 TYMP (0.49) TYMPGPR84
SCHEMBL6571658 0.71 TYMP (0.71) TYMP
SCHEMBL6570517 0.66 TYMP (0.53) TYMP
SCHEMBL8709578 0.63 GPR84 (0.49) TYMPGPR84
Hydrochloric Acid SCHEMBL11753831 0.62 TYMP (0.49) TYMPGPR84
SCHEMBL1690954 0.62 TYMP (1.00) TYMP
SCHEMBL28448729 0.61 TYMP (0.56) TYMP
SCHEMBL11003796 0.60 PKM (0.62) —
SCHEMBL9254063 0.60 GPR84 (0.65) TYMPGPR84
SCHEMBL8592127 0.59 G6PD (0.47) TYMPGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543898-A1 PYRIMIDINE NUCLEOSIDE TREATMENTS The Children's Medical Center Corporation (US) 2025-04-30 — — EP disclosed
WO-2023250015-A1 PYRIMIDINE NUCLEOSIDE TREATMENTS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-12-28 — — WO disclosed
WO-2016142486-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ANTI-ANGIOGENIC RESISTANT CANCER INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE BELLVITGE (IDIBELL) (ES) 2016-09-15 — — WO disclosed
EP-3067369-A1 Methods and compositions for the treatment of anti-angiogenic resistant cancer Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) (ES) 2016-09-14 — — EP disclosed
EP-1625234-B1 BIOSYNTHETIC LABELING AND SEPARATION OF RNA UNIV LELAND STANFORD JUNIOR (US) 2009-08-19 — — EP disclosed
EP-1625234-A4 BIOSYNTHETIC LABELING AND SEPARATION OF RNA UNIV LELAND STANFORD JUNIOR (US) 2007-08-22 — — EP disclosed
EP-1625234-A1 BIOSYNTHETIC LABELING AND SEPARATION OF RNA The Board of Trustees of The Leland Stanford Junior University (US) 2006-02-15 — — EP disclosed
US-20040259135-A1 Biosynthetic labeling and separation of RNA NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-12-23 — — US disclosed
WO-2004101825-A1 BIOSYNTHETIC LABELING AND SEPARATION OF RNA THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2004-11-25 — — WO disclosed
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