Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382571 | 0.84 | ITGB3 (0.42) | NPC1GAAKDM4EALDH1A1TDP1 | |
| SCHEMBL382076 | 0.83 | DRD4 (0.51) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL415668 | 0.80 | DRD4 (0.54) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL415667 | 0.77 | ITGB3 (0.64) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL460323 | 0.76 | ITGB3 (0.41) | TDP1GLAMAPTATM | |
| SCHEMBL7655325 | 0.75 | DRD4 (0.52) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL383213 | 0.75 | DRD4 (0.77) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL383159 | 0.75 | ITGB3 (0.44) | KDM4ETDP1DRD2DRD3GLA | |
| SCHEMBL382073 | 0.74 | DRD4 (0.49) | DRD4NPC1GAAHTR1AADRA2C | |
| SCHEMBL382075 | 0.73 | ITGB3 (0.50) | DRD4NPC1GAAHTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |