Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGAV | P06756 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460323 | 0.91 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKCNH2MAPT | |
| SCHEMBL383159 | 0.84 | ITGB3 (0.44) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL382573 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL382074 | 0.84 | DRD4 (0.51) | ALDH1A1NPC1GAAKDM4EMAPT | |
| SCHEMBL383583 | 0.81 | ITGB3 (0.61) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL382991 | 0.80 | ITGB3 (0.47) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL383467 | 0.79 | CCR5 (0.42) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL382445 | 0.77 | ITGB3 (0.46) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL382483 | 0.77 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL383120 | 0.77 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |