Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.41 |
| ▸ | UBE2M | P61081 | 11/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598395 | 0.76 | GPR119 (0.51) | — | |
| SCHEMBL3757285 | 0.75 | IDO1 (0.44) | CCR5DRD2 | |
| SCHEMBL3757286 | 0.75 | IDO1 (0.44) | CCR5DRD2 | |
| SCHEMBL13052234 | 0.73 | KMT2A (0.43) | DRD2 | |
| SCHEMBL3757466 | 0.72 | CCR5 (0.41) | CCR5DRD2 | |
| SCHEMBL4240911 | 0.72 | CCR5 (0.65) | CCR5 | |
| SCHEMBL3768194 | 0.72 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL3768190 | 0.72 | UBE2M (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL3764142 | 0.72 | CCR5 (0.39) | CCR5DRD2 | |
| SCHEMBL4240711 | 0.70 | CCR5 (0.60) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942890-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORP (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1942890-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2008-07-16 | — | — | EP | disclosed |
| WO-2006138350-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-12-28 | — | — | WO | disclosed |