Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 8/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764142 | 0.89 | CCR5 (0.39) | CCR5UTS2RDRD2SIGMAR1KCNH2 | |
| SCHEMBL3759966 | 0.86 | CCR5 (0.40) | CCR5UTS2RDRD2SIGMAR1KCNH2 | |
| SCHEMBL3756604 | 0.84 | CCR5 (0.40) | CCR5KDM4DGPR88 | |
| SCHEMBL3764215 | 0.83 | CYP3A4 (0.45) | CCR5KDM4DGPR88 | |
| SCHEMBL3757286 | 0.81 | IDO1 (0.44) | CCR5DRD2SIGMAR1 | |
| SCHEMBL3757285 | 0.81 | IDO1 (0.44) | CCR5DRD2SIGMAR1 | |
| SCHEMBL6505071 | 0.79 | ALDH1A1 (0.55) | — | |
| SCHEMBL4597864 | 0.79 | ALDH1A1 (0.55) | — | |
| SCHEMBL5576143 | 0.79 | ALDH1A1 (0.55) | — | |
| SCHEMBL3816009 | 0.79 | CYP3A4 (0.44) | CCR5KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | CCR5 1/4885UTS2R 746/4885DRD2 1693/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | CCR5 1/4885UTS2R 746/4885DRD2 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.