Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.51 |
| ▸ | CNR1 | P21554 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189715 | 1.00 | CNR2 (0.51) | CNR2CNR1MEN1KMT2ATDP1 | |
| SCHEMBL3823354 | 0.87 | CACNA1H (0.40) | CNR2CNR1MEN1KMT2ATDP1 | |
| SCHEMBL3820052 | 0.87 | CACNA1H (0.40) | CNR2CNR1MEN1KMT2ATDP1 | |
| SCHEMBL3819794 | 0.86 | ATM (0.42) | CNR2CNR1TDP1LTB4R2 | |
| SCHEMBL8176408 | 0.86 | ATM (0.42) | CNR2CNR1TDP1LTB4R2 | |
| SCHEMBL3819194 | 0.80 | ATM (0.40) | MEN1KMT2A | |
| SCHEMBL8187625 | 0.79 | TDP1 (0.40) | MEN1KMT2ATDP1LTB4R2 | |
| SCHEMBL3818460 | 0.79 | ALDH1A1 (0.37) | TDP1LTB4R2 | |
| SCHEMBL3819264 | 0.74 | FFAR2 (0.35) | — | |
| SCHEMBL3058165 | 0.72 | CNR2 (0.51) | CNR2CNR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091917-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-08-26 | — | — | EP | claimed |
| WO-2008073934-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |