Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 9/20 | 0.45 |
| ▸ | CD40 | P25942 | 1/20 | 0.42 |
| ▸ | CD40LG | P29965 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780009 | 0.90 | ENPP2 (0.51) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL6050503 | 0.90 | PRMT1 (0.48) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL14004209 | 0.83 | ENPP2 (0.60) | CASP6NT5ECA2CA3ENPP2 | |
| SCHEMBL9507783 | 0.82 | SENP2 (0.54) | CASP6CA2CA3ENPP2AMY1A | |
| SCHEMBL9762407 | 0.82 | SENP2 (0.54) | CASP6CA2CA3ENPP2AMY1A | |
| SCHEMBL3823917 | 0.80 | CASP6 (0.71) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL9236858 | 0.80 | ENPP2 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL8047831 | 0.80 | ENPP2 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL5889361 | 0.80 | ENPP2 (0.49) | CASP6NSD2DUSP3PTPN5PTPN11 | |
| SCHEMBL9236836 | 0.79 | ENPP2 (0.48) | CASP6NSD2DUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614719-B1 | AZO COMPOUND AND SALT THEREOF | NIPPON KAYAKU KK (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-7304147-B2 | Azo compound and salt thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20070079740-A1 | Azo compound and salt thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1614719-A1 | AZO COMPOUND AND SALT THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2006-01-11 | — | — | EP | disclosed |