SCHEMBL3823901

SCHEMBL3823901

CC(CO)(CO)C(=O)NNc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 11/20 0.57
ALOX12 P18054 1/20 0.57
CYP2C19 P33261 1/20 0.57
SMN1; SMN2 Q16637 5/20 0.55
ALOX5 P09917 2/20 0.53
CYP3A4 P08684 1/20 0.53
TSHR P16473 1/20 0.53
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 2/20 0.49
PTGS2 P35354 1/20 0.47
PKM P14618 1/20 0.46
F2 P00734 1/20 0.46
PDK1 Q15118 2/20 0.45
PDK2 Q15119 2/20 0.45
PDK3 Q15120 2/20 0.45
PDK4 Q16654 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10117694 0.92 GAA (0.56) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL19883125 0.82 GAA (0.61) GAACYP2C19CYP3A4ALDH1A1
SCHEMBL6637261 0.81 GAA (0.62) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL13619073 0.75 GAA (0.56) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL10340033 0.75 GAA (0.41) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL2231647 0.73 GAA (0.58) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL10888912 0.73 ALOX5 (0.61) GAAALOX12CYP2C19SMN1; SMN2ALOX5
Phenylhydrazine SCHEMBL10340034 0.71 CYP1A2 (0.50) GAACYP2C19SMN1; SMN2ALOX5CYP3A4
SCHEMBL10172577 0.70 ALOX5 (0.57) GAAALOX12CYP2C19SMN1; SMN2ALOX5
SCHEMBL3295838 0.70 PDK1 (0.61) GAASMN1; SMN2TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US disclosed
EP-2285773-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2017-12-20 EP disclosed
US-8106141-B2 Cure accelerators for anaerobic curable compositions HENKEL CORPORATION (US) 2012-01-31 US disclosed
WO-2009137444-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
EP-0990946-B1 Heat-developable photosensitive material FUJIFILM CORP (JP) 2009-09-09 EP disclosed
EP-1020760-B1 Heat developable image recording material FUJIFILM CORP (JP) 2007-11-14 EP disclosed
EP-1026545-B1 Heat developable photosensitive material FUJIFILM CORP (JP) 2007-09-26 EP disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
EP-0974866-B1 Heat-developable image-recording material FUJI PHOTO FILM CO LTD (JP) 2006-10-18 EP disclosed
EP-0911690-A1 Photothermographic elements adapted for laser exposure FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP disclosed
EP-0911692-A2 Photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP disclosed
EP-0903629-A1 HEAT DEVELOPING PHOTOSENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
EP-0902322-A1 Thermographic image-recording elements FUJI PHOTO FILM CO., LTD. (JP) 1999-03-17 EP disclosed
US-5869229-A HIGH SENSITIVITY IN INFRARED REGION AND A MINIMAL SENSITIVITY CHANGE WITH VARYING STORAGE CONDITIONS FUJI PHOTO FILM CO., LTD. (JP) 1999-02-09 US disclosed
EP-0887701-A1 Method for preparing photosensitive image forming medium coating solution, and photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1998-12-30 EP disclosed
EP-0883022-A1 Coating method for thermographic imaging element, coating solution for thermographic image forming layer, thermographic imaging element, and photothermographic imaging element FUJI PHOTO FILM CO., LTD. (JP) 1998-12-09 EP disclosed
EP-0838722-A2 Photothermographic material, novel 2,3-dihydrothiazole derivative, and photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0829753-A1 Photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-18 EP disclosed
EP-0599463-A2 High speed, dry processed printing plate construction MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions ACLY, ACAD9, CCNY GAA 851/4885ALOX12 1333/4885CYP2C19 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.