Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823901 | 0.81 | GAA (0.57) | GAAALOX5CYP3A4TSHRALOX12 | |
| SCHEMBL13619073 | 0.81 | GAA (0.56) | GAAALOX5CYP3A4TSHRALOX12 | |
| SCHEMBL2231647 | 0.79 | GAA (0.58) | GAAALOX5CYP3A4TSHRALOX12 | |
| SCHEMBL9771265 | 0.79 | L3MBTL1 (0.59) | CYP3A4TSHRCYP2C19KDM4EALDH1A1 | |
| SCHEMBL83110 | 0.78 | L3MBTL1 (0.78) | TSHRALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL6638890 | 0.78 | LMNA (0.55) | GAAALOX12CYP2C19KDM4EALDH1A1 | |
| SCHEMBL19318495 | 0.78 | TSHR (0.58) | GAACYP3A4TSHRCYP2C19KDM4E | |
| SCHEMBL2887835 | 0.77 | PTGS2 (0.57) | GAAKDM4EALDH1A1SMN1; SMN2PTGS2 | |
| SCHEMBL10117694 | 0.77 | GAA (0.56) | GAAALOX5CYP3A4TSHRALOX12 | |
| SCHEMBL10172577 | 0.76 | ALOX5 (0.57) | GAAALOX5CYP3A4TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |