Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339144 | 0.82 | ESR1 (0.59) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL9524242 | 0.82 | ESR1 (0.59) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL1639933 | 0.74 | RAB9A (0.49) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL9695246 | 0.73 | ESR1 (0.59) | ESR1ESR2CA2KDM4EALDH1A1 | |
| Hordenine SCHEMBL19896488 | 0.73 | HRH3 (0.67) | ESR1ESR2CA2KDM4EALDH1A1 | |
| Hordenine SCHEMBL36798 | 0.73 | HRH3 (0.67) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL69344 | 0.72 | ESR1 (1.00) | ESR1ESR2CA2KDM4EALDH1A1 | |
| SCHEMBL3873458 | 0.72 | ESR1 (1.00) | ESR1ESR2CA2KDM4EALDH1A1 | |
| Hordenine SCHEMBL11147428 | 0.71 | HRH3 (0.64) | ESR1ESR2CA2KDM4EALDH1A1 | |
| Hordenine SCHEMBL2478680 | 0.71 | HRH3 (0.64) | ESR1ESR2CA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585976-B2 | Automated radiolabelling method | GE HEALTHCARE LIMITED (GB) | 2017-03-07 | — | — | US | disclosed |
| EP-1933885-B1 | AUTOMATED RADIOLABELLING METHOD | GE HEALTHCARE LTD (GB) | 2009-08-19 | — | — | EP | disclosed |
| US-20080226552-A1 | Disposal cassettes; iodine labels | GE HEALTHCARE LIMITED (GB) | 2008-09-18 | — | — | US | disclosed |
| EP-1933885-A2 | AUTOMATED RADIOLABELLING METHOD | GE Healthcare Limited (GB) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042791-A2 | AUTOMATED RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226552-A1 | Disposal cassettes; iodine labels | SSTR5, SSTR1, TSHR | ESR1 2716/4885ESR2 2730/4885CA2 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.