Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hordenine SCHEMBL19896488 | 1.00 | HRH3 (0.67) | HRH3TAAR1ESR1ESR2CA2 | |
| Hordenine SCHEMBL11147428 | 0.98 | HRH3 (0.64) | HRH3TAAR1ESR1ESR2CA2 | |
| Hordenine SCHEMBL2478680 | 0.98 | HRH3 (0.64) | HRH3TAAR1ESR1ESR2CA2 | |
| Hordenine SCHEMBL28644842 | 0.96 | HRH3 (0.61) | HRH3TAAR1ESR1ESR2CA2 | |
| Hordenine SCHEMBL18329336 | 0.90 | HRH3 (0.55) | HRH3TAAR1ESR1ESR2CA2 | |
| Hordenine SCHEMBL6338584 | 0.90 | HRH3 (0.55) | HRH3TAAR1ESR1ESR2CA2 | |
| SCHEMBL18762839 | 0.87 | HRH3 (0.84) | HRH3TAAR1ALDH1A1CYP2C19SIGMAR1 | |
| Hordenine SCHEMBL18329338 | 0.87 | HRH3 (0.52) | HRH3TAAR1ESR1ESR2CA2 | |
| SCHEMBL2475962 | 0.86 | ESR1 (0.55) | HRH3TAAR1ESR1ESR2CA2 | |
| SCHEMBL28508133 | 0.85 | SIGMAR1 (0.62) | HRH3ESR1ESR2CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746864-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION | Keto Innovations, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| US-20260132413-A1 | AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME | WISCONSIN ALUMNI RES FOUNDATION (US) | 2026-05-14 | — | — | US | claimed |
| EP-4514146-B1 | A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID | BAR ON B V (BE) | 2026-05-13 | — | — | EP | claimed |
| EP-4712954-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR THERAPEUTIC AND PERFORMANCE SUPPLEMENTATION | Keto Innovations, LLC (US) | 2026-03-25 | — | — | EP | claimed |
| US-20250268845-A1 | BONE REGENERATION COMPOSITION INCLUDING HORDENINE AND USE THEREOF | NEWPATHBIO INC. (KR) | 2025-08-28 | — | — | US | claimed |
| US-20250243350-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | TOYO TIRE CORPORATION (JP) | 2025-07-31 | — | — | US | claimed |
| US-20250243345-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | TOYO TIRE CORPORATION (JP) | 2025-07-31 | — | — | US | claimed |
| WO-2025136556-A1 | COMPOSITIONS AND METHODS FOR MINIMIZING EFFECTS OF ALCOHOL INTOXICATION | SAFETY SHOT, INC. (US) | 2025-06-26 | — | — | WO | claimed |
| WO-2025133198-A1 | ANTI-GREY HAIR CARE COMPOSITIONS | UNILEVER IP HOLDINGS B.V. (NL) | 2025-06-26 | — | — | WO | claimed |
| CN-120081885-A | Substituted phenyl glycoside compound and preparation method and application thereof | 浙江大学 | 2025-06-03 | — | — | CN | claimed |
| EP-0885008-A1 | THE REGULATION OF APPETITE, BODY WEIGHT AND ATHLETIC FUNCTION WITH MATERIALS DERIVED FROM CITRUS VARIETIES | Jones, Dennis (US) | 1998-12-23 | — | — | EP | claimed |
| WO-1998014200-A1 | THE REGULATION OF APPETITE, BODY WEIGHT AND ATHLETIC FUNCTION WITH MATERIALS DERIVED FROM CITRUS VARIETIES | JONES DENNIS (US) | 1998-04-09 | — | — | WO | claimed |
| US-4929248-A | CROSSLINKED WITH EPOXY RESIN | KANEBO CO., LTD. (JP) | 1990-05-29 | — | — | US | claimed |
| EP-0145323-B1 | TOUGHENED EPOXY COMPOSITION | LOCTITE CORPORATION (US) | 1988-05-11 | — | — | EP | claimed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0145323-A2 | Toughened epoxy composition | LOCTITE CORPORATION (US) | 1985-06-19 | — | — | EP | claimed |
| US-4435613-A | Semiconductor packing composition for an undersea cable, a cable containing said substance and a method of manufacturing such a cable | LES CABLES DE LYON (FR) | 1984-03-06 | — | — | US | claimed |
| US-4340681-A | Process for the manufacture of foamed or non-foamed compositions | REUTER TECHNOLOGIE GMBH (DE) | 1982-07-20 | — | — | US | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| EP-0033542-A2 | Thermoplastic molding composition, epoxide-vinyl ester resin composition and method for making same | PHILLIPS PETROLEUM COMPANY (US) | 1981-08-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132413-A1 | AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME | PNP, RNGTT, DPYD | HRH3 4066/4885TAAR1 2815/4885ESR1 2632/4885 |
| US-20250268845-A1 | BONE REGENERATION COMPOSITION INCLUDING HORDENINE AND USE THEREOF | SOST, BMP4, HCAR3 | HRH3 57/4885TAAR1 2640/4885ESR1 3852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.