Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | DRD3 | P35462 | 7/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383159 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382447 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6499251 | 0.82 | SFRP1 (0.42) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL383161 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6800344 | 0.81 | DRD2 (0.43) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL381766 | 0.81 | DRD2 (0.42) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6500444 | 0.80 | KAT6A (0.39) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382621 | 0.80 | DRD2 (0.40) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382417 | 0.80 | DRD2 (0.40) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6498423 | 0.80 | DRD2 (0.40) | ITGB3ITGA2BITGAVDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |