Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 4/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499277 | 0.91 | SFRP1 (0.41) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382447 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6500480 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL423056 | 0.89 | ITGB3 (0.40) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL6498464 | 0.89 | DRD2 (0.39) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL383098 | 0.88 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL6501648 | 0.88 | KAT6A (0.39) | ITGB3ITGA2BITGAVDRD2DRD3 | |
| SCHEMBL382826 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BITGAVMAPTATM | |
| SCHEMBL6497874 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BITGAVATM | |
| SCHEMBL382623 | 0.87 | DRD2 (0.40) | ITGB3ITGA2BITGAVDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |