Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109234 | 0.81 | MEN1 (0.36) | MEN1KMT2ABCL2L1BADPTGS1 | |
| SCHEMBL6603955 | 0.81 | SMN1; SMN2 (0.37) | MEN1KMT2AHTTALDH1A1HPGD | |
| SCHEMBL5268107 | 0.77 | ALDH1A1 (0.42) | MEN1KMT2ANOTUMHTTALDH1A1 | |
| SCHEMBL13221420 | 0.68 | MAPK14 (0.40) | MEN1KMT2ABCL2L1BADPTGS1 | |
| SCHEMBL5215863 | 0.67 | CYP3A4 (0.43) | BCL2L1BADPTGS1HTTUSP2 | |
| SCHEMBL9616659 | 0.65 | POLB (0.37) | MEN1KMT2APTGS1PGRALDH1A1 | |
| SCHEMBL29074500 | 0.64 | ACHE (0.56) | MEN1KMT2APTGS1 | |
| SCHEMBL7255766 | 0.62 | NOTUM (0.42) | NOTUMGRM2ALDH1A1MAPT | |
| SCHEMBL5233154 | 0.62 | PTGS1 (0.36) | PTGS1PGRNOTUMHTTUSP2 | |
| SCHEMBL7255969 | 0.62 | CTRC (0.39) | MEN1KMT2APTGS1PGRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885703-A4 | PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES | MICROBIA INC (US) | 2009-09-02 | — | — | EP | disclosed |
| US-20090099355-A1 | Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids | MICROBIA, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20090099355-A1 | Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids | MICROBIA, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20090099355-A1 | Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids | MICROBIA, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20080287663-A1 | Process For Production Of 4-Biphenylyazetidin-2-Ones | MICROBIA, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287663-A1 | Process For Production Of 4-Biphenylyazetidin-2-Ones | MICROBIA, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080287663-A1 | Process For Production Of 4-Biphenylyazetidin-2-Ones | MICROBIA, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080200669-A1 | Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones | MICROBIA, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20080200669-A1 | Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones | MICROBIA, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20080200669-A1 | Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones | MICROBIA, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| CN-101222950-A | Processes for production of 4-(biphenylyl)azetidin-2-one phosphonic acids | MICROBIA INC (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-101218213-A | Process for preparing phenolic 4-biphenylylazetidin-2-ones | MICROBIA INC (US) | 2008-07-09 | — | — | CN | disclosed |
| EP-1896135-A2 | PROCESSES FOR PRODUCTION OF 4-(BIPHENYLYL)AZETIDIN-2-ONE PHOSPHONIC ACIDS | Microbia, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| EP-1893571-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | Microbia Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| EP-1885703-A2 | PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006127893-A2 | PROCESSES FOR PRODUCTION OF 4-(BIPHENYLYL)AZETIDIN-2-ONE PHOSPHONIC ACIDS | MICROBIA, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006122020-A2 | PROCESS FOR PRODUCTION OF 4-BIPHENYLYAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| WO-2006122216-A2 | PROCESSES FOR PRODUCTION OF PHENOLIC 4-BIPHENYLYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287663-A1 | Process For Production Of 4-Biphenylyazetidin-2-Ones | CYP4Z1, CYP4F12, CYP4F2 | MEN1 3240/4885KMT2A 1795/4885BCL2L1 2464/4885 |
| US-20080200669-A1 | Processes For Production of Phenolic 4-Biphenylylazetidin-2-Ones | CYP4B1, CYP4F2, CYP4F12 | MEN1 4223/4885KMT2A 2452/4885BCL2L1 1537/4885 |
| US-20090099355-A1 | Processes for Production of 4-(Biphenylyl)Azetidin-2-One Phosphonic Acids | PIK3CA, PPA1, PIK3CB | MEN1 1235/4885KMT2A 3699/4885BCL2L1 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.