Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1L | O00429 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3829987 | 0.99 | DNM1L (0.44) | DNM1LALDH1A1HSD17B10MAPT | |
| SCHEMBL3826390 | 0.90 | MAPT (0.50) | DNM1LALDH1A1MAPTRECQL | |
| SCHEMBL4734488 | 0.84 | DNM1L (0.42) | DNM1LALDH1A1HSD17B10MAPT | |
| SCHEMBL8170740 | 0.83 | SMN1; SMN2 (0.45) | DNM1LALDH1A1MAPT | |
| SCHEMBL8189719 | 0.82 | CYP1A2 (0.41) | DNM1LALDH1A1MAPT | |
| SCHEMBL3065981 | 0.81 | DNM1L (0.41) | DNM1LALDH1A1MAPT | |
| SCHEMBL3063304 | 0.81 | DNM1L (0.41) | DNM1LALDH1A1MAPT | |
| SCHEMBL3053794 | 0.81 | DNM1L (0.41) | DNM1LALDH1A1MAPT | |
| SCHEMBL3829564 | 0.81 | ALDH1A1 (0.46) | DNM1LALDH1A1HSD17B10MAPTRECQL | |
| SCHEMBL3821644 | 0.80 | LMNA (0.49) | DNM1LALDH1A1HSD17B10MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | claimed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| EP-2097379-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073936-A1 | CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |