Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992958 | 0.98 | NPY1R (0.42) | NPY1RHTTNPY2RALDH1A1SMN1; SMN2 | |
| SCHEMBL3994493 | 0.96 | OPRM1 (0.43) | NPY1RHTTNPY2ROPRM1OPRL1 | |
| SCHEMBL3822905 | 0.96 | OPRM1 (0.43) | NPY1RHTTNPY2ROPRM1OPRL1 | |
| SCHEMBL3995682 | 0.96 | OPRM1 (0.43) | NPY1RHTTNPY2ROPRM1OPRL1 | |
| SCHEMBL3822529 | 0.96 | OPRM1 (0.43) | NPY1RHTTNPY2ROPRM1OPRL1 | |
| SCHEMBL3994478 | 0.96 | OPRM1 (0.43) | NPY1RHTTNPY2ROPRM1OPRL1 | |
| SCHEMBL3821321 | 0.86 | OPRM1 (0.56) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL3822308 | 0.86 | OPRM1 (0.40) | OPRM1OPRL1MEN1KMT2ALMNA | |
| SCHEMBL3824513 | 0.86 | KMT2A (0.43) | OPRM1OPRL1KMT2AOPRD1OPRK1 | |
| SCHEMBL3444264 | 0.85 | CNR2 (0.44) | NPY1RHTTNPY2RALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496890-B1 | SUBSTITUTED BETA-AMINOALCOHOLS USED AS MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2009-09-02 | — | — | EP | claimed |
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2005-01-27 | — | — | US | claimed |
| EP-1496890-B1 | SUBSTITUTED BETA-AMINOALCOHOLS USED AS MEDICAMENTS | GRUENENTHAL GMBH (DE) | 2009-09-02 | — | — | EP | disclosed |
| US-7507816-B2 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | GRUENENTHAL GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020691-A1 | Pharmaceutical preparations comprising substituted beta-aminoalcohols | ADRB1, ADRB2, ADRA1D | NPY1R 1383/4885HTT 2983/4885NPY2R 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.