SCHEMBL3825698

SCHEMBL3825698

CCCC(OS(C)(=O)=O)OS(C)(=O)=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
CA1 P00915 2/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
HDAC3 O15379 2/20 0.33
HDAC4 P56524 2/20 0.33
HDAC1 Q13547 2/20 0.33
HDAC7 Q8WUI4 2/20 0.33
HDAC2 Q92769 2/20 0.33
HDAC10 Q969S8 2/20 0.33
HDAC11 Q96DB2 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
HDAC9 Q9UKV0 2/20 0.33
HDAC5 Q9UQL6 2/20 0.33
USP2 O75604 2/20 0.32
TSHR P16473 2/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848723 0.85 ALDH1A1 (0.40) ALDH1A1CA1CA12CA2CA7
SCHEMBL5281509 0.83 SMPD1 (0.44) ALDH1A1CA1CA12CA2CA7
SCHEMBL5273914 0.81 SMPD1 (0.47) CA1CA12CA2CA7CA14
SCHEMBL5278349 0.81 SMPD1 (0.47) CA1CA12CA2CA7CA14
SCHEMBL27291509 0.80 ALDH1A1 (0.40) ALDH1A1CA1CA12CA2CA7
SCHEMBL14779173 0.79 ALDH1A1 (0.43) ALDH1A1CA1CA12CA2CA7
SCHEMBL4998468 0.79 ALDH1A1 (0.43) ALDH1A1CA1CA12CA2CA7
SCHEMBL28760408 0.77 ALDH1A1 (0.48) ALDH1A1CA1CA12CA2CA7
SCHEMBL28376461 0.77 ALDH1A1 (0.42) ALDH1A1USP2TSHR
SCHEMBL4446331 0.77 ALDH1A1 (0.48) ALDH1A1CA1CA12CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3238709-B1 IMPROVED PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME PLATFORM BRIGHTWORKS TWO LTD (US) 2020-07-01 EP claimed
EP-3238709-A1 IMPROVED PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME PLATFORM BRIGHTWORKS TWO, LTD. (US) 2017-11-01 EP claimed
EP-2701684-B1 IMPROVED PARENTERAL FORMULATIONS OF LIPOPHILIC PHARMACEUTICAL AGENTS AND METHODS FOR PREPARING AND USING THE SAME PLATFORM BRIGHTWORKS TWO LTD (US) 2017-06-14 EP claimed
US-6927001-B1 Non-aqueous electrolytic solution and lithium secondary battery UBE INDUSTRIES, LTD. (JP) 2005-08-09 US claimed
US-10665897-B2 Lithium secondary battery including phosphite additive SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-05-26 US disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
CN-105503732-B For absorbing SO2Double imidazole ion liquids of ether and preparation method thereof and application method 河北科技大学 2018-08-10 CN disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP disclosed
US-20180053967-A1 LITHIUM SECONDARY BATTERY INCLUDING PHOSPHITE ADDITIVE SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-22 US disclosed
CN-105498452-B For absorbing SO2Double imidazole ion liquids of support type ether and preparation method thereof and application method 河北科技大学 2018-02-06 CN disclosed
US-20030026801-A1 Methods for enhancing antibody-induced cell lysis and treating cancer PFIZER INC. 2003-02-06 US disclosed
EP-1280907-A2 METHOD OF MODULATING ACTIVATION OF LYMPHOCYTES VIA MODULATION OF PITUITARY TUMOR TRANSFORMING GENE, RELATED SCREEINING METHODS CEDARS-SINAI MEDICAL CENTER (US) 2003-02-05 EP disclosed
EP-1261620-A2 CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION Roche Diagnostics Corporation (US) 2002-12-04 EP disclosed
US-20020156033-A1 Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer COLEY PHARMACEUTICAL GROUP, INC. 2002-10-24 US disclosed
WO-2001088116-A9 METHOD OF MODULATING ACTIVATION OF LYMPHOCYTES VIA MODULATION OF PITUITARY TUMOR TRANSFORMING GENE, RELATED SCREEINING METHODS CEDARS SINAI MEDICAL CENTER (US) 2002-06-06 WO disclosed
WO-2001097843-A2 METHODS FOR ENHANCING ANTIBODY-INDUCED CELL LYSIS AND TREATING CANCER UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2001-12-27 WO disclosed
WO-2001088116-A2 METHOD OF MODULATING ACTIVATION OF LYMPHOCYTES VIA MODULATION OF PITUITARY TUMOR TRANSFORMING GENE, RELATED SCREEINING METHODS CEDARS-SINAI MEDICAL CENTER (US) 2001-11-22 WO disclosed
WO-2001057064-A2 CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION ROCHE DIAGNOSTICS CORPORATION (US) 2001-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A ALDH1A1 1103/4885CA1 2605/4885CA12 1490/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 ALDH1A1 787/4885CA1 2620/4885CA12 1620/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 ALDH1A1 1061/4885CA1 2687/4885CA12 805/4885
US-10665897-B2 Lithium secondary battery including phosphite additive SCO2, NIBAN2, SLC39A11 ALDH1A1 4583/4885CA1 165/4885CA12 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.