Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460322 | 0.90 | ITGB3 (0.40) | KDM4ENPC1ALDH1A1ITGB3ITGAV | |
| SCHEMBL7656383 | 0.85 | ITGB3 (0.44) | SMN1; SMN2KDM4EALDH1A1ITGB3ITGAV | |
| SCHEMBL383158 | 0.85 | ITGB3 (0.44) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL382073 | 0.84 | DRD4 (0.49) | KDM4ENPC1ALDH1A1TSHRGAA | |
| SCHEMBL383582 | 0.82 | ITGB3 (0.59) | NPC1ALDH1A1ITGB3ITGAVITGA2B | |
| SCHEMBL383466 | 0.81 | CCR5 (0.46) | SMN1; SMN2ALDH1A1ITGB3ITGAVITGA2B | |
| SCHEMBL383252 | 0.80 | CASR (0.42) | KDM4EALDH1A1ITGB3ITGAVITGA2B | |
| SCHEMBL383350 | 0.80 | CASR (0.42) | KDM4EALDH1A1ITGB3ITGAVITGA2B | |
| SCHEMBL382573 | 0.78 | ITGB3 (0.43) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL6499244 | 0.78 | CNR1 (0.38) | KDM4EALDH1A1ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |