Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664584 | 0.85 | CCR5 (0.42) | CCR5MAPK8CKS1BSKP1SKP2 | |
| SCHEMBL383158 | 0.85 | ITGB3 (0.44) | HPGDSLMNASMN1; SMN2ALDH1A1ADRB3 | |
| SCHEMBL383350 | 0.82 | CASR (0.42) | HPGDSNAMPTALDH1A1ADRB3ITGB3 | |
| SCHEMBL383252 | 0.82 | CASR (0.42) | HPGDSNAMPTALDH1A1ADRB3ITGB3 | |
| SCHEMBL382570 | 0.81 | SMN1; SMN2 (0.41) | HPGDSSMN1; SMN2ALDH1A1ADRB3ITGB3 | |
| SCHEMBL383582 | 0.81 | ITGB3 (0.59) | HPGDSALDH1A1ADRB3ITGB3ITGAV | |
| SCHEMBL460322 | 0.79 | ITGB3 (0.40) | HPGDSALDH1A1ADRB3ITGB3ITGAV | |
| SCHEMBL6499244 | 0.78 | CNR1 (0.38) | ALDH1A1DRD2ITGB3ITGAVITGA2B | |
| SCHEMBL382657 | 0.78 | ALDH1A1 (0.42) | LMNASMN1; SMN2ALDH1A1ITGB3ITGAV | |
| SCHEMBL383095 | 0.77 | ITGB3 (0.46) | DRD2ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |