Stanolone

Stanolone

SCHEMBL3826115

C[C@]12CCC(=O)CC1CC[C@@H]1[C@@H]2CC[C@]2(C)C(O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SHBG P04278 6/20 1.00
▸ GPBAR1 Q8TDU6 4/20 1.00
▸ CYP19A1 P11511 2/20 1.00
▸ NR3C1 P04150 1/20 1.00
▸ PGR P06401 1/20 1.00
▸ SERPINA6 P08185 1/20 1.00
▸ NR3C2 P08235 1/20 1.00
▸ CYP3A4 P08684 1/20 1.00
▸ AR P10275 1/20 1.00
▸ HSD17B10 Q99714 1/20 1.00
▸ MGAM O43451 1/20 1.00
▸ AKR1B10 O60218 3/20 0.70
▸ AKR1B1 P15121 3/20 0.70
▸ PDK1 Q15118 2/20 0.68
▸ PDK2 Q15119 2/20 0.68
▸ PDK3 Q15120 2/20 0.68
▸ PDK4 Q16654 2/20 0.68
▸ POLB P06746 1/20 0.66
▸ MAPK1 P28482 1/20 0.66
▸ OR51E2 Q9H255 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Stanolone SCHEMBL14154693 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL11654234 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL15163 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL24684703 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL13172965 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL24410503 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL15963443 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL5534749 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL21442439 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR
Stanolone SCHEMBL12991785 1.00 SHBG (1.00) SHBGGPBAR1CYP19A1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202413-B2 Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for GABA type-A receptors WASHINGTON UNIVERSITY (US) 2019-02-12 — — US disclosed
CN-107873030-A 5‑HT2CReceptor agonists and compositions and methods of use 艾尼纳制药公司 2018-04-03 — — CN disclosed
US-20160251391-A9 NEUROACTIVE ENANTIOMERIC 15-, 16- AND 17-SUBSTITUTED STEROIDS AS MODULATORS FOR GABA TYPE-A RECEPTORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-09-01 — — US disclosed
US-20150361125-A1 NEUROACTIVE ENANTIOMERIC 15-, 16- AND 17-SUBSTITUTED STEROIDS AS MODULATORS FOR GABA TYPE-A RECEPTORS UNIV WASHINGTON (US) 2015-12-17 — — US disclosed
US-9114163-B2 Medication against breast cancer and related diseases MABEL GMBH (DE) 2015-08-25 — — US disclosed
EP-2018170-B1 Medication against breast cancer MABEL GMBH (DE) 2012-07-25 — — EP disclosed
WO-2008100161-A9 SURFACE PLASMON RESONANCE ASSAY FOR STEROIDS THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2009-09-11 — — WO disclosed
US-20090111784-A1 MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES CURADIS GMBH (DE) 2009-04-30 — — US disclosed
US-20090104122-A1 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (mAR) AGENTS MEDEXIS S.A. (GR) 2009-04-23 — — US disclosed
EP-2018170-A2 MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES Teichmann, Alexander Tobias (DE) 2009-01-28 — — EP disclosed
EP-2008099-A2 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (MAR) AGENTS Medexis S.A. (GR) 2008-12-31 — — EP disclosed
WO-2008100161-A1 SURFACE PLASMON RESONANCE ASSAY FOR STEROIDS THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED (NZ) 2008-08-21 — — WO disclosed
WO-2007131737-A2 MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES TEICHMANN ALEXANDER TOBIAS (DE) 2007-11-22 — — WO disclosed
WO-2007123682-A2 DETECTION OF MEMBRANE ANDROGEN RECEPTOR (MAR) AGENTS MEDEXIS S.A. (GR) 2007-11-01 — — WO disclosed
WO-2000066613-A1 BONE TARGETING AGENTS FOR OSTEOPOROSIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2000-11-09 — — WO disclosed
US-4181669-A A CARBODIIMIDE WITH ACID CATALYSTS AS A CONDENSATION AGENT AKTIEBOLAGET LEO (SE) 1980-01-01 — — US disclosed
US-4180504-A Method for the preparation of esters AKTIEBOLAGET LEO (SE) 1979-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111784-A1 MEDICATION AGAINST BREAST CANCER AND RELATED DISEASES CYP19A1, SHBG, ESRRB SHBG 2/4885GPBAR1 32/4885CYP19A1 1/4885
US-20150361125-A1 NEUROACTIVE ENANTIOMERIC 15-, 16- AND 17-SUBSTITUTED STEROIDS AS MODULATORS FOR GABA TYPE-A RECEPTORS GABRA4, GABRA5, GABRA3 SHBG 190/4885GPBAR1 117/4885CYP19A1 300/4885
US-10202413-B2 Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for GABA type-A receptors GABRA4, GABRA5, GABRA3 SHBG 190/4885GPBAR1 117/4885CYP19A1 300/4885
US-20160251391-A9 NEUROACTIVE ENANTIOMERIC 15-, 16- AND 17-SUBSTITUTED STEROIDS AS MODULATORS FOR GABA TYPE-A RECEPTORS GABRA4, GABRA5, GABRA3 SHBG 190/4885GPBAR1 117/4885CYP19A1 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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