Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | DRD3 | P35462 | 7/20 | 0.40 |
| ▸ | CASR | P41180 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382117 | 0.82 | DRD2 (0.44) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6796559 | 0.78 | CASR (0.45) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL383016 | 0.78 | DRD2 (0.55) | DRD2DRD3CASRUSP2 | |
| SCHEMBL382964 | 0.77 | CASR (0.45) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6796240 | 0.76 | DRD2 (0.43) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6796554 | 0.76 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL382962 | 0.75 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL28747046 | 0.75 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6800173 | 0.74 | CASR (0.43) | ITGB3ITGAVITGA2BITGB1ITGA5 | |
| SCHEMBL6796225 | 0.74 | CASR (0.44) | ITGB3ITGAVITGA2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |