Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775070 | 1.00 | ALDH1A1 (0.46) | ALDH1A1RAPGEF4LMNAGAANPSR1 | |
| SCHEMBL2775069 | 1.00 | ALDH1A1 (0.46) | ALDH1A1RAPGEF4LMNAGAANPSR1 | |
| Glycine SCHEMBL11349154 | 0.90 | LMNA (0.50) | ALDH1A1RAPGEF4LMNAGAANPSR1 | |
| SCHEMBL1422067 | 0.86 | CYTH2 (0.42) | ALDH1A1 | |
| SCHEMBL1422066 | 0.86 | CYTH2 (0.42) | ALDH1A1 | |
| SCHEMBL27243575 | 0.84 | ALDH1A1 (0.46) | ALDH1A1RAPGEF4LMNAGAAHTT | |
| SCHEMBL11705334 | 0.81 | TSHR (0.43) | ALDH1A1RAPGEF4LMNAHTTTSHR | |
| SCHEMBL11202735 | 0.81 | PYGL (0.46) | ALDH1A1RAPGEF4LMNAGAANPSR1 | |
| SCHEMBL11056093 | 0.81 | PYGL (0.46) | ALDH1A1RAPGEF4LMNAGAANPSR1 | |
| Glycine SCHEMBL11339724 | 0.80 | LMNA (0.44) | ALDH1A1LMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101861299-A | Stereoselective Preparation of Amino Acid Derivatives | BCN PEPTIDES SA | 2010-10-13 | — | — | CN | disclosed |
| WO-2009065987-A3 | METHOD FOR THE STEREOSELECTIVE PREPARATION OF AMINO ACID DERIVATIVES | BCN PEPTIDES SA (ES) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009065987-A2 | METHOD FOR THE STEREOSELECTIVE PREPARATION OF AMINO ACID DERIVATIVES | BCN PEPTIDES S.A. (ES) | 2009-05-28 | — | — | WO | disclosed |