Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.65 |
| ▸ | ITGAV | P06756 | 12/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383238 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL382653 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL7654735 | 0.83 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL382643 | 0.83 | ITGB3 (0.52) | ITGB3ITGAVITGA2BALDH1A1VDR | |
| SCHEMBL382860 | 0.83 | ITGB3 (0.92) | ITGB3ITGAVITGA2B | |
| SCHEMBL7469287 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGA2BVDR | |
| SCHEMBL7655214 | 0.81 | KDM4E (0.48) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL382656 | 0.80 | ITGB3 (0.63) | ITGB3ITGAVITGA2BLMNAPKM | |
| SCHEMBL27360304 | 0.80 | ITGB3 (0.66) | ITGB3ITGAVITGA2B | |
| SCHEMBL382861 | 0.80 | ITGB3 (0.68) | ITGB3ITGAVITGA2BLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |