Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048223 | 0.93 | PPARA (0.44) | SYKKLK5KLK7CTSSCTSL | |
| SCHEMBL19694832 | 0.83 | KYNU (0.56) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL19694834 | 0.83 | KYNU (0.56) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL4256075 | 0.83 | KYNU (0.56) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL3826896 | 0.79 | CTSS (0.41) | SYKCTSSCTSLCTSBMEN1 | |
| SCHEMBL14190228 | 0.78 | CTSL (0.61) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL29398102 | 0.78 | SYK (0.57) | SYKKLK5KLK7CTSSCTSL | |
| SCHEMBL19327506 | 0.78 | KLK5 (0.51) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL19327507 | 0.78 | KLK5 (0.51) | SYKKLK5KLK7KYNUCTSS | |
| SCHEMBL5870038 | 0.77 | KLK5 (0.64) | SYKKLK5KLK7KYNUCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625153-B1 | ACYLATED LYSOBACTIN-TYPE NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-08-26 | — | — | EP | disclosed |