Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523979 | 0.77 | L3MBTL1 (0.52) | ALDH1A1KDM4ETSHRHSD17B10HPGD | |
| SCHEMBL3951574 | 0.75 | MEN1 (0.41) | MAPTALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4318402 | 0.75 | ALDH1A1 (0.46) | MAPTALDH1A1GAAKDM4ETSHR | |
| Bicarbonate SCHEMBL7346713 | 0.71 | HPGD (0.51) | MAPTALDH1A1GAAKDM4ETSHR | |
| SCHEMBL2417969 | 0.71 | ALDH1A1 (0.49) | MAPTALDH1A1GAAKDM4ETSHR | |
| SCHEMBL29728559 | 0.71 | PTPN1 (0.49) | MAPTALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31108964 | 0.70 | KIF11 (0.51) | ALDH1A1KDM4EMEN1KMT2A | |
| Bicarbonate SCHEMBL7346726 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1GAAKDM4ETSHR | |
| Bicarbonate SCHEMBL7346716 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1GAAKDM4ETSHR | |
| SCHEMBL28080111 | 0.70 | KDM4E (0.49) | MAPTALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765339-A4 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-09-02 | — | — | EP | disclosed |
| EP-1765339-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005057-A2 | MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | disclosed |