Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 3/20 | 0.51 |
| ▸ | CASP6 | P55212 | 3/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485998 | 0.88 | CASP6 (0.57) | NSD2CASP6PTPN11DUSP3PTPN5 | |
| SCHEMBL6050503 | 0.83 | PRMT1 (0.48) | NSD2CASP6PTPN11DUSP3PTPN5 | |
| SCHEMBL112101 | 0.81 | EGFR (0.69) | EGFRNSD2CASP6CYP2C9HSD17B10 | |
| SCHEMBL29378452 | 0.81 | EGFR (0.69) | EGFRNSD2CASP6CYP2C9HSD17B10 | |
| SCHEMBL112102 | 0.81 | EGFR (0.69) | EGFRNSD2CASP6CYP2C9HSD17B10 | |
| SCHEMBL3201337 | 0.80 | CASP6 (0.70) | NSD2CASP6PTPN11DUSP3PTPN5 | |
| SCHEMBL3823917 | 0.80 | CASP6 (0.71) | NSD2CASP6PTPN11DUSP3PTPN5 | |
| SCHEMBL144370 | 0.79 | EGFR (0.67) | EGFRNSD2CASP6CYP2C9HSD17B10 | |
| SCHEMBL144372 | 0.79 | EGFR (0.67) | EGFRNSD2CASP6CYP2C9HSD17B10 | |
| SCHEMBL2438105 | 0.79 | PRMT1 (0.60) | EGFRNSD2CASP6PTPN11DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614719-B1 | AZO COMPOUND AND SALT THEREOF | NIPPON KAYAKU KK (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-7304147-B2 | Azo compound and salt thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20070079740-A1 | Azo compound and salt thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1614719-A1 | AZO COMPOUND AND SALT THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2006-01-11 | — | — | EP | disclosed |