Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGAV | P06756 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383372 | 0.86 | ITGB3 (0.42) | ITGB3ITGAVITGA2BVDRNPY2R | |
| SCHEMBL383238 | 0.85 | ITGB3 (0.52) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL382677 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL384052 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BHPGDGAA | |
| SCHEMBL382643 | 0.82 | ITGB3 (0.52) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7544324 | 0.82 | ITGB3 (0.42) | ITGB3ITGAVITGA2BVDRNPY2R | |
| SCHEMBL7469287 | 0.79 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL6797582 | 0.79 | ITGB3 (0.41) | ITGB3ITGAVITGA2BVDRNPY2R | |
| SCHEMBL382456 | 0.79 | ITGB3 (0.47) | ITGB3ITGAVITGA2BVDRNPY2R | |
| SCHEMBL382848 | 0.78 | ITGB3 (0.42) | ITGB3ITGAVITGA2BNPY2RMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |