Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.45 |
| ▸ | ITGAV | P06756 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383238 | 0.94 | ITGB3 (0.52) | ITGB3ITGAVITGA2BVDRKDM4E | |
| SCHEMBL381838 | 0.90 | ITGB3 (0.51) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL382643 | 0.89 | ITGB3 (0.52) | ITGB3ITGAVITGA2BVDRKDM4E | |
| SCHEMBL383051 | 0.88 | ITGB3 (0.54) | ITGB3ITGAVITGA2BHTT | |
| SCHEMBL382763 | 0.87 | ITGB3 (0.48) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7469099 | 0.87 | KAT6A (0.41) | ITGB3ITGAVITGA2BEPHX2 | |
| SCHEMBL7457979 | 0.87 | SFRP1 (0.42) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7470713 | 0.86 | KAT6A (0.39) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL7464227 | 0.86 | ITGB3 (0.37) | ITGB3ITGAVITGA2BKDM4EHTT | |
| SCHEMBL382204 | 0.86 | ITGB3 (0.39) | ITGB3ITGAVITGA2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | claimed |
| EP-1229024-A1 | m-SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING INTEGRIN ALPHA-V BETA-3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-08-07 | — | — | EP | disclosed |