Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471269 | 0.91 | MEN1 (0.37) | ITGB3ITGAVITGA2BKDM1AMAOA | |
| SCHEMBL382568 | 0.90 | ITGB3 (0.43) | ITGB3ITGAVITGA2BMAPTSMN1; SMN2 | |
| SCHEMBL382409 | 0.88 | KDM4E (0.40) | ITGB3ITGAVMAPTGAAKMT2A | |
| SCHEMBL7662184 | 0.88 | KDM4E (0.46) | KDM1AMAOAKDM1BRCOR1ALDH1A1 | |
| SCHEMBL382612 | 0.87 | GAA (0.37) | ITGB3ITGAVALDH1A1LMNAMAPT | |
| SCHEMBL7467073 | 0.87 | VCP (0.41) | ITGB3ITGAVGAAKMT2AGRIN2B | |
| SCHEMBL382677 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVITGA2BSMN1; SMN2GAA | |
| SCHEMBL382399 | 0.84 | ITGB3 (0.40) | ITGB3ITGAVITGA2BALDH1A1LMNA | |
| SCHEMBL383372 | 0.84 | ITGB3 (0.42) | ITGB3ITGAVITGA2BSMN1; SMN2GAA | |
| SCHEMBL382847 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVITGA2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | claimed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-6420558-B1 | COMPOUNDS WITH AMIDINE GROUPS ANTAGONISTIC ACTIVITY, CELL ADHESION INHIBITORY ACTIVITY, HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY, AND THERAPEUTIC AGENTS | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1074543-A1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2001-02-07 | — | — | EP | disclosed |