Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091557 | 0.82 | UGT2B7 (0.50) | UGT2B7AOC3MMP9SLC6A2SLC6A4 | |
| SCHEMBL890238 | 0.80 | PGR (0.49) | OPRD1KCNH2GLACYP1A2CYP2D6 | |
| SCHEMBL14816808 | 0.80 | PGR (0.49) | OPRD1KCNH2GLACYP1A2CYP2D6 | |
| SCHEMBL7259343 | 0.75 | HDAC4 (0.44) | AOC3OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL3971799 | 0.75 | ACHE (0.44) | UGT2B7MMP9SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7261194 | 0.73 | BRD4 (0.50) | AOC3OPRM1OPRD1SLC6A4SLC6A3 | |
| SCHEMBL7255569 | 0.73 | HPGD (0.42) | AOC3MEN1KMT2ATSHR | |
| SCHEMBL11626007 | 0.73 | UGT2B7 (0.47) | UGT2B7AOC3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19042004 | 0.73 | UGT2B7 (0.60) | UGT2B7AOC3MMP9SLC6A2SLC6A4 | |
| SCHEMBL15695558 | 0.73 | UGT2B7 (0.60) | UGT2B7MMP9CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099762-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008068266-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-06-12 | — | — | WO | disclosed |