Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978356 | 0.76 | UGT2B7 (0.43) | ACHEUTS2RUGT2B7MEN1KMT2A | |
| SCHEMBL3973220 | 0.76 | UGT2B7 (0.43) | ACHEUTS2RUGT2B7MEN1KMT2A | |
| SCHEMBL3976615 | 0.75 | SLC6A2 (0.39) | ACHEUTS2RUGT2B7MEN1KMT2A | |
| SCHEMBL6091557 | 0.75 | UGT2B7 (0.50) | UTS2RUGT2B7MEN1KMT2AMMP9 | |
| SCHEMBL3828872 | 0.75 | UGT2B7 (0.46) | UTS2RUGT2B7MEN1KMT2ACYP2D6 | |
| SCHEMBL8080369 | 0.70 | AOC3 (0.57) | UGT2B7MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7055439 | 0.70 | ALDH1A1 (0.45) | UTS2RUGT2B7MEN1KMT2ACYP3A4 | |
| SCHEMBL15695558 | 0.70 | UGT2B7 (0.60) | UGT2B7MMP9TSHR | |
| SCHEMBL2203728 | 0.69 | FFAR1 (0.57) | UGT2B7MEN1KMT2ACYP2D6MMP9 | |
| SCHEMBL10299134 | 0.69 | PGR (0.41) | MEN1KMT2ACYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051661-A2 | SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGS AND USES THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2009-04-23 | — | — | WO | disclosed |