Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 7/20 | 0.57 |
| ▸ | HRH1 | P35367 | 7/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.56 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814672 | 0.93 | L3MBTL1 (0.63) | L3MBTL1NPC1MAPTMMP1HRH2 | |
| SCHEMBL3811266 | 0.88 | L3MBTL1 (0.59) | L3MBTL1NPC1MAPTMMP1HRH2 | |
| SCHEMBL8754539 | 0.87 | THRA (0.65) | L3MBTL1MMP1HRH2HRH1THRB | |
| SCHEMBL28875657 | 0.86 | L3MBTL1 (0.66) | L3MBTL1MMP1HRH2HRH1THRB | |
| SCHEMBL28315253 | 0.86 | L3MBTL1 (0.66) | L3MBTL1MMP1HRH2HRH1THRB | |
| SCHEMBL9172925 | 0.84 | MMP1 (0.58) | L3MBTL1NPC1MAPTMMP1THRB | |
| SCHEMBL9042605 | 0.84 | L3MBTL1 (0.59) | L3MBTL1MAPTSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL11440823 | 0.83 | L3MBTL1 (0.76) | L3MBTL1NPC1MMP1HRH2HRH1 | |
| SCHEMBL1373310 | 0.83 | L3MBTL1 (0.57) | L3MBTL1NPC1MAPTMMP1HRH2 | |
| SCHEMBL7370624 | 0.82 | PARP10 (0.63) | L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951217-A4 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2009-08-12 | — | — | EP | disclosed |
| US-20080234199-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-25 | — | — | US | disclosed |
| EP-1951217-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062148-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234199-A1 | Chemical Compounds | GPER1, ESR2, ESR1 | L3MBTL1 4673/4885NPC1 717/4885MAPT 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.