Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | CDK9 | P50750 | 4/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383135 | 0.91 | ITGB3 (0.43) | ITGB3ITGAVITGA2B | |
| SCHEMBL381718 | 0.89 | ALDH1A1 (0.38) | ITGB3ITGAVITGA2BCCNT1CCNA2 | |
| SCHEMBL382907 | 0.88 | GRIN2B (0.35) | ITGB3ITGAVCCNT1CCNA2CDK2 | |
| SCHEMBL6499236 | 0.88 | CNR1 (0.37) | KMT2AALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL384052 | 0.84 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKMT2AALDH1A1 | |
| SCHEMBL383372 | 0.84 | ITGB3 (0.42) | ITGB3ITGAVITGA2BHPGDSMN1; SMN2 | |
| SCHEMBL382456 | 0.83 | ITGB3 (0.47) | ITGB3ITGAVITGA2BALDH1A1MAPT | |
| SCHEMBL382401 | 0.83 | ITGB3 (0.46) | ITGB3ITGAVITGA2BKMT2AALDH1A1 | |
| SCHEMBL7544324 | 0.81 | ITGB3 (0.42) | ITGB3ITGAVITGA2BKMT2AALDH1A1 | |
| SCHEMBL383437 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVITGA2BKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-1074543-B1 | AMINOPIPERIDINE DERIVATIVES AS INTEGRIN ALPHA V BETA 3 ANTAGONISTS | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-01-25 | — | — | EP | disclosed |